Call for Papers

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Davide Gabellini's picture
Davide Gabellini
Post date: 
08/10/2019 - 11:42


Frontiers in Physiology

Topic: Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases

Despite having distinct embryonic origins, cardiac and skeletal muscle share many structural and functional features, both in physiological and pathological terms. When it comes to diseases, many single-gene cardiac disorders have been identified but in most cardiopathic patients the underlying causes have a multifactorial basis, in which life-style factors play a preeminent role. Skeletal muscle can also be affected by a relatively large number of Mendelian diseases, but it is involved in a smaller range of acquired disorders, most notably cancer-related cachexia and ageing-related sarcopenia. This article collection will focus on studies (including original research, perspectives, mini-reviews and opinion papers) that deal with the molecular mechanisms underlying the different pathologies, both inherited and acquired, that affect heart and skeletal muscle, as well as the in vitro and in vivo models that can be used to study them.

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Libero Vitiello, University of Padova, Italy

Marcella Canton, University of Padova, Italy

Martina Calore, Maastricht University, Netherlands