Exciting postdoctoral opportunity to evaluate a novel RNA based therapeutic strategy
Monday, 31. December 2018
Exciting postdoctoral opportunity to evaluate a novel RNA based therapeutic strategy
Employer: Human Molecular Genetic laboratory, International Centre for Genetic Engineering and Biotechnology
Location: Trieste, Italy
Posted: October 8, 2018
Discipline: Life sciences, RNA biology, gene therapy
Organization Type: International Research Centre, Academic
Job Type: NIH-funded PostDoc
An NIH-funded postdoctoral position is immediately available in Dr. F. Pagani’s laboratory in ICGEB, Trieste, Italy for highly motivated candidates who are interested in RNA
based therapies to correct splicing defects.
The Human Molecular Genetics lab studies the molecular mechanisms of pre-mRNA processing defects in human diseases and has developed a therapeutic strategy to correct
aberrant splicing based on modified U1 snRNP https://www.icgeb.org/human-moleculargenetics.
This strategy is applied through AAV and lentiviral vectors in cellular and animal models to correct splicing defects. The candidate is expected to evaluate the efficacy
of the RNA based strategy in relevant animal models, analyze off targets and contribute to define the molecular mechanism involved in the splicing rescue. Successful candidates will
have a background in RNA biology. Prior experience in animal studies, neuropathology and RNA-SEQ/bioinformatic analysis will be a plus. The gross annual salary will be of
41.200$ (~35.000 Euro).
Applicants should submit an application package that includes a cover letter, CV, relevant prior publications, and contact information for three references to
Pagani Franco, at pagani@icgeb.org . Application review will begin immediately and continue until the position is filled.
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